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Antibody–drug conjugates (ADCs) are a revolutionary strategy in targeted therapy, merging the specificity of monoclonal antibodies (mAbs) with powerful payloads for the delivery of therapeutic drugs to disease locations

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Interestingly significantly increased BRET was observed between adenosine A 2A and FGF1 following concomitant agonist stimulation [43], consistent with previous biochemical observations in PC12 adrenal medulla cells where synergistic ERK1/2 phosphorylation was only observed with dual activation of A 2A and FGFR-1 [44]